CCTG IC.8: Immunization With IMM-101 vs Observation for Prevention of Respiratory and Severe COVID-19 Related Infections in Cancer Patients at Increased Risk of Exposure (COV-IMMUNO). The CCTG IC8 trial has closed to accrual, for additional information please visit the IC8 CCTG trial page The purpose of the trial was to find out if immunization with a new immune-stimulator will prevent or reduce severe respiratory and COVID-19 infections in cancer patients. A new type of immune stimulating therapy is being developed for the treatment of cancer. It works by activating the parts of your immune system involved with protecting against viral and bacterial infections.