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CCTG Connection



Published:
Category: Group updates
CCTG Pharmacy Network seeking Western Representative
The CCTG Pharmacy Network is actively seeking western pharmacy representation for the Pharmacy Network Steering Group Read More

Published:
Category: Group updates
Trial-specific DSMC Summary Reports are now posted

Trial-specific DSMC Summary Reports are now posted on trial webpages. Single-study centres participating on these trials should download these reports and submit them to their Research Ethics Boards if required by local policy. Trials currently under CCTG's DSMC oversight include:

 

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Published:
Category: Group updates
2026 Annual Spring Meeting of Participants is fast approaching!

Funded invitations to the CCTG Annual Spring Meeting of Participants have been sent!

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Published:
Category: News
ESMO updates clinical practice guidelines based on CO21 results
The European Society for Medical Oncology has updated its clinical practice guidelines to formally recommend integrating structured exercise into the standard of care for patients following their colon cancer treatment. This change is the direct result of the 17 year CCTG CO21 CHALLENGE trial that showed that guided exercise can improve survival rates and reduce cancer recurrence. Read More

Published:
Category: Publications
Publication: General review HIV Eligibility in Canadian Cancer Clinical Trials
People living with HIV have historically been excluded from many cancer clinical trials, limiting their access to new therapies and reducing the generalizability of research. Recent recommendations from professional societies encourage broader inclusion. Read More

Published:
Category: Publications
Publication: CRC2 sub study
Tissue-Free Circulating Tumor DNA Assay and Patient Outcome in a Phase III Trial of FOLFOX-Based Adjuvant Chemotherapy, Detection of molecular residual disease using circulating tumor DNA (ctDNA) may enable postoperative risk stratification and guide adjuvant therapy. Read More

Published:
Category: Publications
Publication: General review OPTIMISE-ROR
International Consensus-Driven Recommendations for Patient-Reported Outcome Research Objectives in Early Phase Dose-Finding Oncology Trials: Read More

Published:
Category: Trials
Trial closure:  two IND241 sub studies
There have been permanent closures of two IND241 sub studies: IND241 B: A Phase II Study of RP-6306 in Patients with CDK4/6-Inhibitor Treated ER+HER2- Metastatic Breast Cancer Receiving Gemcitabine IND241 D: A Phase II Study of Lunresertib Plus Camonsertib in Patients With CDK4/6 Inhibitor Treated ER+/HER2- Metastatic Breast Cancer Read More