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CCTG Connection



Published:
Category: Group updates

Published:
Category: Publications
Publication: GA1 secondary analysis

Older adults with resectable gastric cancer undergoing perioperative chemotherapy or preoperative chemoradiotherapy plus perioperative chemotherapy: A secondary analysis of the AGITG TOPGEAR phase III trial

This secondary analysis evaluated the treatment adherence, adverse events, and survival in older (≥70 years) adults undergoing perioperative treatment for gastric cancer.

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Published:
Category: Publications
Publication: PA7 substudy
Clinical and Molecular Correlates of Circulating Tumor Fraction in Patients with Metastatic Pancreatic Ductal Adenocarcinoma
 
Pre-existing and emerging molecular targeted therapies have been identified for the treatment of pancreatic ductal adenocarcinoma (PDAC) and exemplify the need for incorporating tumor sequencing into routine clinical practice. Tumor profiling through circulating tumor DNA (ctDNA) represents an important opportunity in PDAC because of the aggressive nature of the disease.
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Published:
Category: Trials
Trial closure:  ME.10

The ME.10 Phase III Randomized Study of Four Weeks High Dose IFN-a2b in Stage T2b N0, T3a-bN0, T4a-b N0, and T1-4, N1a, 2a (microscopic) Melanoma trial has permanently closed.

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Published:
Category: Trials
Trial closure:  BR31
The BR.31 Phase III Prospective Double Blind Placebo Controlled Randomized Study of Adjuvant MEDI4736 in Completely Resected Non-Small Cell Lung Cancer has permanently closed. The purpose of this study was to find out whether it is better to receive a new drug, MEDI4736, or better to receive no further treatment after surgery (and possibly chemotherapy) for lung cancer.
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Published:
Category: Group updates
Remote Consent aligned with GCP R3
As discussed at Spring Meeting and the recent CRA lunch and learn, CCTG's position on remote consent, aligned with GCP R3, is now posted on the Consent Form Policies page.
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Published:
Category: News
The Quality of Life Committee is currently seeking new committee members
The Quality of Life (QOL) Committee is currently seeking two individuals with enthusiastic interest in the measurement of patient-reported outcomes (PROs) in cancer clinical trials. One will focus on brain cancer and one on supportive care. Ideal candidates would have either formal methodologic training in measurement sciences or equivalent experience, and one or both should be active in PRO science research. Experience in the field of oncology is highly desirable. Read More

Published:
Category: Publications
Publication: substudy MA32
Exploration of body mass index and circulating metabolic factors as predictors of metformin benefit in the Canadian Cancer Trials Group MA.32 Read More