Skip to main content

CCTG Connection



Published:
Category: Publications
Publication: IND240A and IND240B

An immunotherapy platform study in platinum-resistant high grade serous ovarian cancer (IPROC): Sub-studies A and B: Durvalumab (D) + mecbotamab vedotin (BA3011) or ozuriftamab vedotin (BA3021)

Read More

Published:
Category: Publications
Publication:  mature results CE5
Temozolomide Versus Radiotherapy as First-Line Therapy for Low-Grade Glioma: Mature Results of a Randomized Phase III Trial (EORTC 22033-26033)
Prognosis in low-grade gliomas (LGGs) remains highly variable, and treatment-related late toxicity is a concern.
Read More

Published:
Category: Trials
Closed to Accrual: MA39
"The MA.39 trial exemplifies the ability of the NCTN to undertake rigorously designed and conducted patient centred trials which address patient values and cancer outcomes," says Dr. Wendy Parulekar the studies Senior Investigator. "Data collection continues on all participants and we are grateful to our collaborators for their ongoing support of this important trial." Read More

Published:
Category: Trials
Closed to Accrual: SC.28 SEAMLESS

The SC.28 SEAMLESS Study: A Pragmatic Multi-Site Randomized Waitlist-Controlled Trial of a Smartphone App-Based Mindfulness Intervention for French and English Speaker Cancer Survivors has closed to accrual with 300 participants randomized to the study. 

Read More



Published:
Category: Group updates
Volunteer CRA needed: CCTG Hematology Committee

The Canadian Cancer Trials Group is actively seeking a CRA representatives from Canadian Member sites to sit on the Hematology Disease Site Committee. 

Disease site committees are composed of representatives from centres participating in CCTG trials. They oversee the status and progress of CCTG trials in their portfolio, including discussion and review of proposals of new studies for recommendation to the Clinical Trials Committee (CTC). Each committee has a chair and an executive.

Read More

Published:
Category: News
CCTG, EORTC and UK3CR welcome G7 commitment to accelerate global progress against cancer

The Canadian Cancer Trials Group (CCTG), the European Organisation for Research and Treatment of Cancer (EORTC), and the UK Collaborative for Cancer Clinical Research (UK3CR) welcome the G7 Leaders’ announcement recognizing cancer as a global priority and calling for stronger international cooperation to improve outcomes for patients[i].

Read More

Published:
Category: Publications
Publication: LY18 Cohort A primary publication
Although chimeric antigen receptor T-cell therapy has supplanted autologous stem cell transplantation (ASCT) for most patients with relapsed/refractory (R/R) diffuse large B-cell lymphoma after 1 line of therapy, ASCT may still be a suitable therapy for some patients, especially those with late relapse. Read More

Published:
Category: Publications
Publication: General review Strengthening Biomarker Research in CCTG Trials
Pathology is essential to modern cancer clinical trials, especially those that use tumour tissue to decide who can join, what treatment they receive, or whether the treatment is working. However, internal data from the Canadian Cancer Trials Group (CCTG) show that in many trials, tissue samples are either not sent in at all or sent as slides instead of the preferred tissue blocks—sometimes affecting 30–50% of patients depending on the cancer type. Read More