Wednesday, February 18, 2026 People Living with HIV Eligibility in Canadian Cancer Clinical Trials People living with HIV have historically been excluded from many cancer clinical trials, limiting their access to new therapies and reducing the generalizability of research. Recent recommendations from professional societies encourage broader inclusion. The extent to which Canadian trials follow these guidelines has not been described. In this study, we reviewed 136 cancer trials conducted with the Canadian Cancer Trials Group and found that most did not restrict participation of people living with HIV. However, some trial protocols still excluded them without justification. Trials using immune checkpoint inhibitor therapies, and those run with industry support, were more likely to exclude people living with HIV. Greater inclusion could help ensure equitable access to research, guide policy updates, and support more representative cancer studies in Canada. Comelles MF, Perez-Patrigeon S, Senneker T, Johnson A, Hicks LK, Balneaves L, Chen BE, Hay AE. People Living with HIV Eligibility in Canadian Cancer Clinical Trials. Current Oncology 33: 102. 2026.https://www.mdpi.com/1718-7729/33/2/102
