CCTG has opened the anticipated international brain cancer study CCTG CE9 (LUMOS2) - joining forces with the Australian Cooperative Trials Group for Neuro-Oncology (COGNO) to make enrollment accessible to Canadian patients.
Radiotherapy to Block (CURB2) Oligoprogression In Metastatic Non-Small-Cell Lung Cancer
STRIDE (durvalumab + tremelimumab) with Lenvatinib vs STRIDE Alone in Patients with Unresectable Hepatocellular Carcinoma (SLIDE-HCC)
Addition of Docetaxel to Androgen Receptor Pathway Inhibitors in Patients with Metastatic Castration Sensitive Prostate Cancer and Suboptimal PSA Response (TRIPLE-SWITCH)
Neoadjuvant Immunotherapy with Response-Adapted Treatment vs Standard-Of-Care Treatment For Resectable Stage III/IV Cutaneous Squamous Cell Carcinoma
The CCTG ES3 NEEDS international esophageal cancer clinical trial is now opened in Canada. The study is investigating whether delaying surgery for patients with squamous cell carcinoma of the esophagus is as good as the current treatment.
Eradicating MRD in Patients with AML prior to Stem Cell Transplant (ERASE)
VIGOR: Vorasidenib as Maintenance Treatment after First-line Chemoradiotherapy in IDH-mutant Grade 2 or 3 Astrocytoma
Botensilimab + Balstilimab vs Best Supportive Care as Therapy in Chemo-refractory, Advanced, Colorectal Adenocarcinoma: The BATTMAN Trial
Delayed Reduced Volume and Dose Elective Ratiotherapy (REVERT) in Patients with HNSCC
CALMS: Combination Therapy with Luspatercept in Lower Risk MDS CTEP approval: 2024AUG27 (date of US Steering Committee Evaluation)
Selective Index Node Resection vs Lymph Node Dissection after Neoadjuvant Immunotherapy for Stage IIIB-D Melanoma The Multicentre Selective Lymphadenectomy Trial-3 (MSLT-3)
The CCTG HN.9 study has been centrally activated in Canada, as of January 31.
HN.9 is a Randomized Phase II Study of Cisplatin plus Radiotherapy versus Durvalumab plus Radiotherapy followed by Adjuvant Durvalumab versus Durvalumab plus Radiotherapy followed by Adjuvant Tremelimumab and Durvalumab in Intermediate Risk HPV-Positive Locoregionally Advanced Oropharyngeal Squamous Cell Cancer (LA-OSCC), 2018.
The Canadian Cancer Trials Group is actively seeking CRA representatives from Canadian Member sites to sit on the Lung Disease Site Committee Executive and the Quality of Life Committee.
The 2018 Clinical Trials Conference hosted by CTO – taking place March 27-28, 2018 at the Sheraton Hotel in Toronto – is an interactive and collaborative 2-day event that brings together over 350 people from industry, research, ethics, healthcare, non-profit, government and academia to exchange ideas, build relationships, and develop new strategies with respect to improving clinical trials and bringing more clinical trials to Ontario.
The Cancer Research Institute (CRI) and the Canadian Cancer Trials Group (CCTG) have announced a multi-year collaboration to develop and conduct clinical trials in immunotherapy. There is an urgent need to collaborate on clinical trials and translational research and to unite leading experts.
The preferred candidates will have a combination of academic and clinical experience, with demonstrated clinical expertise in family medicine, will exhibit strong potential for innovative and scholarly research, and provide evidence of an ability to work in an interdisciplinary, collaborative environment. Clinical responsibilities will be based at the Queen’s Family Health Team in Kingston and include taking call approximately one (1) night per month and three (3) weekends per year.
Online citations of previously published CCTG studies MA.27 and OV.21
CCTG is pleased to announce that Dr. Martin Smoragiewicz has joined the group as a Senior Investigator. Dr. Smoragiewicz is a medical oncologist who completed his undergraduate BSc and MD.CM at McGill University, and internal medicine and medical oncology training in British Columbia. He has completed a fellowship in early phase clinical trials at the University of Cambridge, focusing on immune approaches in pancreatic cancer as part of a PhD program. Dr. Smoragiewicz will be working with Lesley Seymour in the IND program.
The Quality of Life committee is currently seeking 2-3 individuals with enthusiastic interest in the measurement of patient-reported outcomes in clinical trials.
