For nearly half of people diagnosed with lung cancer, immunotherapy can slow the disease but not stop it. Funded through a $4 million joint investment from the Canadian Cancer Society (CCS) and the Weston Family Foundation, a new clinical trial aims to change that.
Venetoclax and HMA-based Therapies for the Treatment of Older and Unfit Adults with Newly Diagnosed FLT3-mutated AML: A myeloMATCH Treatment Trial
VIGOR: Vorasidenib as Maintenance Treatment after First-line Chemoradiotherapy in IDH-mutant Grade 2 or 3 Astrocytoma
Autologous Stem Cell Transplant in Peripheral T Cell Lymphoma that Achieved a First Complete Remission (CR1) Following Induction Therapy (PTCL-STAT)
Lanreotide for the Prevention of Postoperative Pancreatic Fistula
The CCTG ES3 NEEDS international esophageal cancer clinical trial is now opened in Canada. The study is investigating whether delaying surgery for patients with squamous cell carcinoma of the esophagus is as good as the current treatment.
Phase II Trial of ASTX727 and Venetoclax Compared with ASTX727, Venetoclax, and Enasidenib for New Diagnosed Older Adults with IDH2 Mutant AML - A myeloMATCH Substudy
Eradicating MRD in Patients with AML prior to Stem Cell Transplant (ERASE)
LUNA-2: LND101 in Unresectable Non-Small Cell Lung Cancer: A Randomized Phase II Trial
RAINBO-ORANGE: Treatment of Endometrial Cancer Based On Molecular Features
Delayed Reduced Volume and Dose Elective Radiotherapy (REVERT) in Patients with HNSCC
No Chemotherapy in Intermediate-risk HR + HER2- Early Breast Cancer Treated with Ribociclib (NoLEEta)
The next CCTG Clinical Research Associate (CRA) Lunch and Learn training session will be on Wednesday Jun 24th, 2025, at 12 pm ET, covering the top
The MYC2 trial (SWOG S1803) - A Phase III Study of Daratumumab/rHuPH20 (NSC- 810307) + Lenalidomide or Lenalidomide as Post-Autologous Stem Cell Transplant Maintenance Therapy in Patients with Multiple Myeloma (MM) Using Minimal Residual Disease to Direct Therapy Duration (DRAMMATIC Study) - has closed Step #1 registration of new study participants having successfully reach the target accrual goal (n=1420 for Screening Step). Step #2 and Step #3 remain open.
Above: Dr. Rahima Jamal and Camille Amiel prepare the patient to take the fecal microbiota capsules. Photo: Centre hospitalier de l’Université de Montréal (CHUM)
français: La période d’inscription à l’essai novateur sur le mélanome ME17 est commencée.
The CCTG Gastro-Intestinal Disease Site Committee would like to recognize Dr Vincent Barrette and Dr Anthony Lott for their accrual contributions to the CRC10 study as new investigators.
CCTG will be holding the next CRA Lunch and Learn on Wednesday January 22nd, 2025, at 12 pm ET. Session 2 will cover the topic of CCTG Website Navigation and Communications.
MA41 trial investigating a de-Escalation of adjuvant chemotherapy in HER-2 positive, estrogen receptor-negative, node-negative, early breast cancer patients who achieved pathological complete response after neoadjuvant chemotherapy and dual HER-2 blockade (DECRESCENDO) trial has now permanently closed.
