CCTG has opened the anticipated international brain cancer study CCTG CE9 (LUMOS2) - joining forces with the Australian Cooperative Trials Group for Neuro-Oncology (COGNO) to make enrollment accessible to Canadian patients.
Radiotherapy to Block (CURB2) Oligoprogression In Metastatic Non-Small-Cell Lung Cancer
STRIDE (durvalumab + tremelimumab) with Lenvatinib vs STRIDE Alone in Patients with Unresectable Hepatocellular Carcinoma (SLIDE-HCC)
LND101 for Fecal Microbiota Transplantation in Combination with Immune Checkpoint Blockade in Patients with Advanced Melanoma
Addition of Docetaxel to Androgen Receptor Pathway Inhibitors in Patients with Metastatic Castration Sensitive Prostate Cancer and Suboptimal PSA Response (TRIPLE-SWITCH)
The CCTG ES3 NEEDS international esophageal cancer clinical trial is now opened in Canada. The study is investigating whether delaying surgery for patients with squamous cell carcinoma of the esophagus is as good as the current treatment.
Eradicating MRD in Patients with AML prior to Stem Cell Transplant (ERASE)
VIGOR: Vorasidenib as Maintenance Treatment after First-line Chemoradiotherapy in IDH-mutant Grade 2 or 3 Astrocytoma
CO33: Botensilimab + Balstilimab vs Best Supportive Care as Therapy in Chemo-refractory, Advanced, Colorectal Adenocarcinoma: The BATTMAN Trial
Delayed Reduced Volume and Dose Elective Ratiotherapy (REVERT) in Patients with HNSCC
CALMS: Combination Therapy with Luspatercept in Lower Risk MDS CTEP approval: 2024AUG27 (date of US Steering Committee Evaluation)
The MA36 study team would like to thank everyone who helped them reach the 34 patient accrual goal for this important study.
MA36 is a Randomised, Double-Blind, Parallel group, Placebo-Controlled Multicenter Phase III Study to Assess the Efficacy and Safety of Olaparib versus Placebo as Adjuvant Treatment in Patients with Germline BRCA1/2 Mutations and High Risk HER2 Negative Primary Breast Cancer Who Have Completed Definitive Local Treatment and Neoadjuvant or Adjuvant Chemotherapy.
Please be aware that there have been training updates for the Good Clinical Practice Revision 2 implementation. As background, GCP Revision 2 was approved by the ICH regulatory committee November 6, 2016 and Health Canada will implement Revision 2 April 1st, 2019. CCTG communicated a 3 year expiry for GCP certification in spring 2018.
We are fast approaching the CCTG Spring Meeting 2019 #CCTG2019 and here is an update on what you need to know about deadlines and due dates.
Dr. Yee Ung will be stepping down as the CCTG radiation oncology co-chair of the thoracic disease site committee as of April 2019, and we are calling for applicants to this position.
The applicant should be a thoracic oncology staff radiation oncologist practicing in a CCTG member Institution in Canada, with international or national leadership experience in clinical trials.
CCTG would like to say congratulations to our colleagues Ian Tannock and Natasha Leighl both from the Princess Margaret Cancer Centre for their recent recognition by ASCO as 2019 Leaders in Cancer Care
Allen S. Lichter Visionary Leader Award and Lecture
This award was created in honor of Allen. S. Lichter, MD, FASCO, to recognize ASCO members who have transformed the oncology field or significantly advanced the mission of ASCO, the Conquer Cancer Foundation, or CancerLinQ, LLC, through their leadership, vision, and ability to inspire.
We are very saddened to share that our esteemed colleague Dr. Stephen Couban passed away on March 19, 2019 at his home in Halifax.
Stephen was a remarkable leader, everyone at CCTG and across the network are grateful for the years of leadership he provided as the Co-Chair of the Hematology Disease Site Committee and Chair of the Leukemia Subcommittee.
The Canadian Cancer Trials Group 2019 Annual Spring Meeting will be held May 3 - 5, 2019 at the Chelsea Hotel in Toronto. Invitations have been sent and it is now time for you to register!
The CCTG Lay Representatives Committee has been renamed the Patient Representatives Committee.
