For nearly half of people diagnosed with lung cancer, immunotherapy can slow the disease but not stop it. Funded through a $4 million joint investment from the Canadian Cancer Society (CCS) and the Weston Family Foundation, a new clinical trial aims to change that.
Venetoclax and HMA-based Therapies for the Treatment of Older and Unfit Adults with Newly Diagnosed FLT3-mutated AML: A myeloMATCH Treatment Trial
VIGOR: Vorasidenib as Maintenance Treatment after First-line Chemoradiotherapy in IDH-mutant Grade 2 or 3 Astrocytoma
Autologous Stem Cell Transplant in Peripheral T Cell Lymphoma that Achieved a First Complete Remission (CR1) Following Induction Therapy (PTCL-STAT)
Lanreotide for the Prevention of Postoperative Pancreatic Fistula
A new survey study SC32S, collecting sociodemographic data from clinical trial participants, has now opened across Canada. This study will help researchers understand the feasibility of using a survey to gather information about trial participants’ backgrounds and everyday lives.
Phase II Trial of ASTX727 and Venetoclax Compared with ASTX727, Venetoclax, and Enasidenib for New Diagnosed Older Adults with IDH2 Mutant AML - A myeloMATCH Substudy
Eradicating MRD in Patients with AML prior to Stem Cell Transplant (ERASE)
Investigating Precision Medicine in the Adjuvant setting: a phase III Clinical Trial in Biliary tract cancer (SAFIR IMPACT BTC)
LUNA-2: LND101 in Unresectable Non-Small Cell Lung Cancer: A Randomized Phase II Trial
RAINBO-ORANGE: Treatment of Endometrial Cancer Based On Molecular Features
Delayed Reduced Volume and Dose Elective Radiotherapy (REVERT) in Patients with HNSCC
The next CCTG Clinical Research Associate (CRA) Lunch and Learn training session will be on Wednesday Jun 24th, 2025, at 12 pm ET, covering the top
The CCTG HD11 study, a Randomized Phase II Study of Pembrolizumab and Brentuximab Vedotin Versus GDP, Followed by High Dose Chemotherapy and Autologous Stem Cell Transplantation for Relapsed/Refractory Classical Hodgkin Lymphoma has closed to accrual. This purpose of this study was to determine if treatment with Pembrolizumab and Brentuximab vedotin is better or worse than the standard of care for classical Hodgkin lymphoma.
For more information > CCTG HD11 members trial page.
CCTG is upgrading our login platform to Auth0 by Okta for a more secure and seamless login experience. The new login screen is designed to be simple and user-friendly, allowing you to log in using your existing credentials. This change ensures faster, more reliable access to your account with fewer sign ins, while keeping your data safe.
Please join us in congratulating our friend and colleague, Timothy Whelan on his appointment to the Order of Canada. He is a world-class radiation oncologist and his research has redefined radiation therapy’s use in the treatment of breast cancer, improving survival rates and limiting side effects. He has mentored many trainees, solidifying the reputations of McMaster University and the Juravinski Cancer Centre as leaders in oncology clinical trial training.
Congratulations to Dr. Lesley Seymour, CCTG’s IND Program Director and Deputy Director, on being named a Fellow in the Canadian Academy of Health Sciences (CAHS). Election to the Academy is one of the highest honours in the Canadian health sciences community, recognizing individuals for their exceptional contributions to advancing health research, policy, and care.
"I am honoured to be appointed as a CAHS Fellow and delighted that the contributions of Canadian Cancer Trials Group faculty and investigators have been recognized," says Dr. Seymour.
The HE2 (SLIDE-HCC) clinical trial is now open to enrollment and will investigate whether adding an oral anti-angiogenic drug to an existing intravenous immunotherapy combination is more effective than the immunotherapy combination alone for people with liver cancer who have not received prior treatment.
