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CCTG Connection



Published:
Category: Trials
Closed to Accrual: MA41
The MA41 study: De-Escalation of adjuvant ChemotheRapy in HER-2 positive, EStrogen reCEptor-negative, Node-negative, early breast cancer patients who achieved pathological complete response after neoadjuvant chemotherapy and Dual HER-2 blOckade (DECRESCENDO) has closed to accrual. The sponsors Breast International Group and Institut Jules Bordet have decided to close the recruitment of this trial.
 
For more information please visit the MA41 members trial page.
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Published:
Category: Group updates
Patient Representatives Committee updates
Updates from the Patient Representatives Committee; Patient engagement in cancer research in Canada community of practice, patient engagement resources now available and update on membership. Read More

Published:
Category: Group updates
CCTG EDIIA Working Groups still accepting new members!

CCTG is still accepting members for our Equity, Diversity, Inclusivity, Indigenization, Accessibility (EDIIA) Working Groups as we strive to create a more equitable, diverse, inclusive, accessible, and culturally safe community for our network and for our patient participants. 

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Published:
Category: Publications
Publication: MA32 Secondary Analysis and a Colorectal correlative study
MA32 secondary analysis: Effect of Metformin Versus Placebo on New Primary Cancers in Canadian Cancer Trials Group MA.32: A Secondary Analysis of a Phase III Randomized Double-Blind Trial in Early Breast Cancer
 
Goodwin PJ, Chen BE, Gelmon KA, Whelan TJ, Ennis M, Lemieux J, Ligibel JA, Hershman DL, Mayer IA, Hobday TJ, Bliss JM, Rastogi P, Rabaglio-Poretti M, Thompson AM, Rea DW, Stos PM, Shepherd LE, Stambolic V, Parulekar WR.
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Published:
Category: Trials
CCTG SC28 SEAMLESS study is now open in Canada

The CCTG SC28 SEAMLESS study is now open in Canada for anyone who has completed their primary cancer treatment, to learn mindfulness meditation on an app and see if it helps to improve stress and well being

"People who have had cancer may have multiple unmet psychosocial needs after the completion of their primary treatment, and for the first 5 years of surveillance and follow-up. Survivors often report feeling “lost in transition” as they shift back to their previous lives at home and in the workplace," says study chair Dr. Linda Ellen Carlson, Tom Baker Cancer Centre.

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Published:
Category: Trials
CCTG HD12 a hematology trial investigating targeted therapy for early-stage Hodgkin lymphoma opens in Canada

The CCTG HD12 trial is the second study in the RADAR international trial and has recently opened in Canada. Researchers will compare the usual treatment for Hodgkin lymphoma, with a new treatment that takes the standard combination drug treatment replacing one of the drugs with brentuximab vedotin that may be more effective and cause fewer side effects for patients.

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Published:
Category: Publications
BR10, BR11, CO17 and LY12.
Everest L, Chen BE, Hay AE, Cheung MC, Chan KKW. Power and sample size calculation for incremental net benefit in cost effectiveness analyses with applications to trials conducted by the Canadian Cancer Trials Group.
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Published:
Category: Publications
MA37 - Impact of BMI in Patients With Early Hormone Receptor–Positive Breast Cancer Receiving Endocrine Therapy With or Without Palbociclib in the PALLAS Trial
 
Pfeiler G, Hlauschek D, Mayer EL, Deutschmann C, Kacerovsky-Strobl S, Martin M, et al. Impact of BMI in Patients With Early Hormone Receptor–Positive Breast Cancer Receiving Endocrine Therapy With or Without Palbociclib in the PALLAS Trial (ONLINE).
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