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CCTG Connection



Published:
Category: Publications
CCTG MA36: Adjuvant Olaparib for Patients with BRCA1- or BRCA2-Mutated Breast Cancer. Among patients with high-risk, HER2-negative early breast cancer and germline BRCA1 or BRCA2 pathogenic or likely pathogenic variants, adjuvant olaparib after completion of local treatment and neoadjuvant or adjuvant chemotherapy was associated with significantly longer survival free of invasive or distant disease than was placebo. Olaparib had limited effects on global patient-reported quality of life. Read More

Published:
Category: Publications
Statistical publications 1) Predictive significance of an optimized panel for basal-like breast cancer: Results from the Canadian Cancer Trials Group MA.5 and MA.12 phase III clinical trials and 2) Publication on statistical methodology and quality of life: A Joint Model for Longitudinal Outcomes with Potential Floor or Ceiling Effects and Survival Times, with Applications to Analysis of Quality of Life Data from a Cancer Clinical Trial 3) Genome-wide association studies of survival in 1520 cancer patients treated with bevacizumab-containing regimens Read More



Published:
Category: Group updates

Reporting and accountable to the Manager, Early Drug Development Program (EDDP), the Trial Team Leader will lead one of several teams in Trial Management Group (TMG). Teams are comprised primarily of study coordinators, research associates, and clinical trials assistants, who are involved in the coordination of clinical trials in cancer therapy, prevention and supportive care.

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Published:
Category: Group updates

Reporting to the Team Leader, Ethics and Regulatory, the Ethics Research Associate will assist to conduct the ethics responsibilities of the Ethics and Regulatory (ER) office, within the Canadian Cancer Trials Group (CCTG).

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Published:
Category: Publications

CRAFT - A Proposed Framework for Decentralized Clinical Trials Participation in Canada has been published in Current Oncology and is available online:

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Published:
Category: Group updates

David Cescon MD, PhD, is a Medical Oncologist and Clinician Scientist at the Princess Margaret Cancer Centre, where his clinical practice is devoted to the care of patients with breast cancer. His research integrates laboratory and clinical studies, focused on the identification of breast cancer therapeutic vulnerabilities and determinants of drug response and resistance.

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Published:
Category: Group updates

Just a reminder that Canadian Thanksgiving is fast approaching and our central office will be closed on Monday, October 11, 2021. We will reopen Tuesday, October 12, 2021 at 8;30 AM. Enjoy the holiday with your family and friends!

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Published:
Category: Group updates
The Cancer Research Monitor/Auditor will conduct quality control and assurance activities for clinical trials in North America, providing support to both the monitoring and audit programs of the Canadian Cancer Trials Group (CCTG), as required. Read More